News
Dr. Dongwon Lee receives an Early Career Investigator Award from National Ataxia Foundation
02/17/2023
Dr. Dongwon Lee, a postdoctoral fellow in the laboratory of Dr. Mingshan Xue, a principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital and assistant professor at Baylor College of Medicine, was recently selected for an Early Career Investigator Award by the National Ataxia Foundation.
MoreThe therapeutic window for Angelman syndrome patients may be broader than previously reported
02/10/2023
Researchers at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital and Baylor College of Medicine have found that a gene therapy approach can effectively reverse key symptoms of this disorder in adult and juvenile rodent models, which demonstrates that the therapeutic age window for Angelman syndrome is much broader than reported previously and offers a new ray of hope for patients and their families impacted by this devastating disorder.
MoreA new neurodevelopmental epilepsy disorder and its genetic cause discovered
12/16/2022
A recent study from the laboratories of Dr. Hsiao-Tuan Chao, assistant professor at Baylor College of Medicine (BCM) and investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital, and Dr. Pankaj Agrawal, professor at Harvard Medical School and Boston Children’s Hospital, identified alterations in the Eukaryotic Initiation Factor 4A2 (EIF4A2) gene as the cause of a novel DEE syndrome.
MoreDr. Sameer Sheth Announced as Director of The Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories at Texas Children’s Hospital
11/29/2022
Dr. Sameer Sheth, Professor at Baylor College of Medicine, has been named the new Director of the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories within the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital.
MoreAn animal model of West syndrome exhibits a progressive increase in epileptic spasms and learning and memory deficits
11/02/2022
West syndrome, the most prevalent type of syndromic epileptic encephalopathy affecting infants, is a devastating and often fatal condition. It is characterized by a triad of symptoms – seizures/spasms, a signature brain activity between seizure events, and intellectual disabilities.
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