Research at Cain
Progress in unlocking the brain's "code" for depression
03/16/2023
A new study in the journal Biological Psychiatry published by Elsevier advances our understanding of the basic neural circuitry of depression in the human brain. The study was led by the Cain Labs director who is also a professor at Baylor College of Medicine and Duncan NRI investigator, Dr. Sameer Sheth, Dr. Wayne Goodman at Baylor College, and Dr. Nader Pouratian at UT Southwestern Medical Center.
The clinical presentation of IDDMSSD syndrome is likely associated with the molecular location of the mutation in the PAK1 gene
03/16/2023
A recent study from Texas Children’s Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.
A comprehensive circuit mapping study reveals many unexpected facts about the norepinephrine neurons in the brainstem
03/13/2023
A recent pioneering study published in eLife from the laboratory of Dr. Xiaolong Jiang, investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital and assistant professor at Baylor College of Medicine, has revealed the cellular composition and circuit organization of the locus coeruleus in adult mice.