Research at Cain

Recurring seizures Disrupt the Fine Balance of Synaptic Homeostasis

11/13/2014

Excessive and synchronized nerve cell activity has long known to underlie the generation of seizures. A review published in the July 2014 issue of Advances in Experimental Medicine and Biology, proposes a novel hypothesis. It suggests that compensatory mechanisms engaged by the synapses in an epileptic brain to control run-away neuronal hyper-excitation end up having other detrimental and long-term consequences on the functioning of nerve cells, thereby impacting learning and memory.