Progress in unlocking the brain's "code" for depression

A new study in the journal Biological Psychiatry published by Elsevier advances our understanding of the basic neural circuitry of depression in the human brain. The study was led by the Cain Labs director who is also a professor at Baylor College of Medicine and Duncan NRI investigator, Dr. Sameer Sheth, Dr. Wayne Goodman at Baylor College, and Dr. Nader Pouratian at UT Southwestern Medical Center.

“In order to use neuromodulation techniques to treat complex psychiatric or neurological disorders, we ideally need to understand their underlying neurophysiology,” Dr. Sheth said. “We are thrilled to have made initial progress in understanding how mood is encoded in human prefrontal circuits. As more such data become available, we will hopefully be able to identify which patterns are common across individuals and which are specific. This information will be critical in designing and personalizing next-generation therapies for depression such as DBS.”

Read the full news release by Elsevier

- , 03/16/2023