The Foundation for Angelamn Syndrome Therapeutics (FAST) launches a new biotech, GeneTx Biotherapeutics LLC (GeneTx), a subsidiary of FAST, for the development and commercialization of an investigational antisense drug, GTX-101, for the treatment of Angelman syndrome (AS), a rare genetic disorder characterized by epilepsy, impaired motor function and speech delays. Read More
Dr. Anne Anderson, epileptologist at Texas Children's Hospital and investigator at the Cain Labs and Jan and Dan Duncan Neurological Research Institute. Read the blog posted on the Foundation for Angelman Syndrome Therapeutics website that describes Dr. Anderson's latest research findings on Angelman syndrome.
David Cameron’s son Ivan was born with a neurological disorder that baffled doctors. He was later diagnosed with a rare epileptic syndrome, Ohtahara syndrome. Now, he writes, genomic testing can end the anguish of uncertainty.
On International Epilepsy Day (Feb 12th), Texas Children's experts, an epileptologist, Dr. Dave Clarke, Ms. Jillian Davis, lead dietitician for ketogenic diet program and Dr. Rebecca Schultz, pediatric nurse practiitioner, share valuable information about the benefits of ketogenic diet for epilepsy patients.
What is epilepsy, and who is affected?
A study shows that structural alterations in neurons and the resulting memory deficits that arise after a single generalized seizure can be reversed by inhibiting the Phosphoinositide 3-kinase/Akt kinase/mechanistic target of rapamycin (i.e. PI3K/Akt/mTOR) signaling pathway.
A drug initially discovered by the researchers in the Gordon and Mary Cain Foundation for Pediatric Neurology Research at Texas Children’s Hospital to be effective in treating refractory seizures commonly seen in tuberous sclerosis patients is now approved for use in Europe.
A recent study published in eNeuro from the laboratory of Dr. John Swann, director of the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories at Texas Children’s Hospital shows how frequent seizures alter the microanatomy of neurons in the brain and that the activity of a specific enzyme may contribute to the cognitive and behavioral deficits observed in children with epileptic encephalopathies.
“Number of Americans with active epilepsy is increasing,” concludes a national and state-specific study that was published last week in the Center for Disease Control and Prevention (CDC)’s Morbidity and Mortality Report.
Epilepsy, a common neurological disorder characterized by repeated seizures that can involve temporary loss of consciousness, altered or rapid eye movements, involuntary muscular jerks or twitching and other symptoms.