Research at Cain

Many roads to hyperexcitation: mTOR suppressors regulate synaptic function in different ways

11/17/2014

Loss of 2 genes that repress mechanistic Target of Rapamycin (mTOR), a growth-promoting pathway, causes autism and epilepsy. Excessive excitation of neurons was assumed to be the culprit. However, a study published in the February 2014 issue of The Frontiers in Molecular Neuroscience adds a new twist.

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The brain’s balancing act: Researchers at UCSD discover how neurons equalize between excitation and inhibition

11/14/2014

Researchers at the University of California, San Diego School of Medicine have discovered a fundamental mechanism by which the brain maintains its internal balance. 
 

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Cognition and behavior: Seizures may spark social deficits

11/14/2014

Inducing seizures in young mice leads them to show autism-like social deficits, as well as problems with learning and memory, according to a paper published in Experimental Neurology.

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